Saw Palmetto is a palm tree and bush grows on the coasts of North
America, in Florida, South Carolina and Southern California. The extract
has a diuretic, decongestant and anti-inflammatory by others the
5-alpha reductase inhibitor. The 5-alpha reductase interferes with the
metabolism of testosterone within the prostate one. It causes the
conversion of circulating testosterone to dihydro testosterone, which is
active in prostate cells. By inhibiting 5-alpha reductase less dihydro
testosterone (DHT) is produced and inhibited cell growth within the
prostate. Saw palmetto fruit
have no effect on the PSA level and therefore do not affect the
interpretation of results in the prostate cancer screening. This is
important because it must not be interrupted for the taking of PSA
testing.
The symptoms improve sustainable
There
are a number of extensive studies and evidence of efficacy for Sabal
extracts in combination with nettle root extract and pumpkin seed
extract. These drugs are well tolerated and therefore useful in the
long-term therapy applicable. The efficacy of the combination drugs has
been documented in approximately 30 clinical trials involving more than
13,500 people. It was shown that for the BPH syndrome typical symptoms
such as nighttime urination (nocturia), frequent urination, delayed
start of urination, weakened urine flow and dribbling improved
significantly. The effectiveness of combination products is comparable
to the efficacy of finasteride, although occurring much less side
effects, especially rare headache and erectile dysfunction.
Combination products are superior to
Be
applied Sägepalmfrucht combination products in stages I and II of
benign prostatic hyperplasia. The effects of individual components add
and complement each other well. Which are usually well tolerated. Only
in rare cases can lead to mild gastrointestinal complaints.
Nettle root (Urtica dioica)
Nettle root has anti-inflammatory and diuretic
Extracts of nettle root (Urtica dioica) are used against complaints of
micturition in benign prostatic enlargement in stages I and II. They
have an anti-inflammatory and diuretic effect. Due to specific
interactions with growth factors or with membrane receptors, an effect
on cell differentiation and proliferation processes is suspected. A
combination with other herbal ingredients, such as with Saw palmetto fruit makes sense.
The complaints improve significantly
In double-blind studies an improvement in symptoms was demonstrated.
Thereafter, the residual urine decreased and the average urinary flow
rate increased as well as the maximum urinary flow. Also showed a
significant improvement of subjective complaints.
Pumpkin seeds (Cucurbita pepo)
The evaluated improve by 65 percent
The effect of pumpkin seeds or pumpkin seed extracts have been
demonstrated in several studies. There was a significant improvement of
symptoms in the bladder emptying compared with placebo. On the IPSS
scale, a scale for estimating the International
Prostate Symptom Score showed improvements of 65 percent compared to
placebo by 54 percent.
Application in stages I and II of BPH
Pumpkin seed extracts are used for many years with overactive bladder
and urinary symptoms of benign prostate enlargement in stages I and II
to inhibit Prostanglandin synthese. Prostaglandin is a substance
occurring in virtually every organ with diverse properties. In addition
to clearly cytoprotective prostaglandin is involved in functions
including the development of fever, inflammation and pain. For benign
prostate enlargement prostaglandin plays an important role. Pumpkin
seeds have anti-inflammatory, diuretic and antioxidant effects.
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