Germ cell cancer

The incidence of germ cell tumors has increased by 18% from 2000-2006. This trend is not present to influence, since the causes lie in the past 30 years. The mortality rates in East and West Germany have converged in recent years tended to, it remains a significant gap to the disadvantage of East Germany. In the above two points, the causes are unclear. A testicular microlithiasis justifies the presence of risk factors for the formation of germ cell tumors of the testis biopsy. When Nichtseminom in clinical stage I speak to-date data from Sweden for a single cycle of PEB. A study by Ehrlich suggests that in complete remission after first-line chemotherapy (defined as residual tumor <1 cm) a Residualtumorresektion is dispensable.

Recently a rise in the incidence of testicular germ cell cancer (TGCC) has been reported Repeatedly in Germany (18% during the period 2000-2006). Future investigations are needed to examine causes for this increase in TGCT. The mortality rates in the western and eastern parts of Germany converge, but there is still a Significantly higher mortality rate in the eastern part. Again future investigations are needed to examine causes for this phenomenon. In cases of testicular microlithiasis, testicular biopsy should be considered if further testicular dysgenesis syndrome representing factors are present, such as infertility, atrophic testes, and undescended testes. One course of adjuvant BEP reduces the risk of relapse by approximately 90% and may be a new option as the initial treatment for all CS1 NSGCT. Patients obtaining a CR (<1 cm) after first-line chemotherapy can be safely observed without PC-RPLND. Relapse are rare and potentially curable with further treatment.